“The difference for patients taking both antidepressants and Omega 3, compared to a placebo, was highly significant. “Many studies have shown Omega 3s are very good for general brain health and improving mood, but this is the first analysis of studies that looks at using them in combination with antidepressant medication. Omega 3 fish oil has a good track record for joint health and for improving mood but can also be used as a complementary medicine for people on antidepressants. “The strongest finding from our review was that Omega 3 fish oil – in combination with antidepressants – had a statistically significant effect over a placebo,” says Dr Sarris, who heads up the Arcadia Mental Health Research Group looking at nutraceutical, lifestyle factors and plant-based medicines for health. The University of Melbourne’s Dr Jerome Sarris led the National Health and Medical Research Council-funded analysis, published in the American Journal of Psychiatry. University of Melbourne and Harvard researchers examined 40 clinical trials worldwide from the 1960s to today alongside a comprehensive evidence review for using nutrient supplements (known as nutraceuticals) in tandem with common classes of antidepressants. S-adenosylmethionine (SAMe), which is a relatively new synthetic supplement found in chemists, was also found to be beneficial.
The international evidence review reveals fish oils, and Vitamin D, can increase the effectiveness of antidepressants used to treat clinical depression. Omega 3 supplements can give antidepressants a boost, particularly in those people who don’t respond well to the medication, a new study has found.
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